The Karumathampatti to Salem bus route covers approximately 142 kms and takes about 2 hrs 13 mins. A total of 17 direct buses operated by 8 bus operators run on this route. The first bus departs at 00:25, and the last bus leaves at 23:55.
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Major boarding points in Karumathampatti include Karumathampatti, while common drop locations in Salem are Attur, Avr Roundana, Ayodhiyapatinam, Kondalampatti, Mettupatti, Omalur, Salem New Bus Stand, Seelanaickenpatti, Valappadi, Vinayaka Mission University.
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RTC and private operators such as SNB Travels, Paradizo travels, Sri Skandha Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 600 - INR 2999.00 depending on the bus type and features.



