The Thalassery to Thalayolaparambu bus route covers approximately 276 kms and takes about 6 hrs 55 mins. A total of 14 direct buses operated by 8 bus operators run on this route. The first bus departs at 00:20, and the last bus leaves at 23:15.
Major boarding points in Thalassery include Chala Bypass, Dharmadam, Edakkad, Kunhippally, Madappally (Nadapuram Road), Mahe, Muzhuppilangadu, Thalaserry, Thalassery, Thalassery Co-operative Hospital, while common drop locations in Thalayolaparambu are Appanchira, Arayankavu, Kanjiramattam, Poothotta, Thalayolaparambu, kaduthuruthy.
RTC and private operators such as Jacobs Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 600 - INR 1400.00 depending on the bus type and features.



