The Thrissur Bypass to Salem bus route covers approximately 294 kms and takes about 4 hrs 16 mins. A total of 14 direct buses operated by 9 bus operators run on this route. The first bus departs at 21:10, and the last bus leaves at 23:50.
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Major boarding points in Thrissur Bypass include Kadavanthara, Manuthy Pass, while common drop locations in Salem are Avr Roundana, Omalur, Others, Peramanur, Salem New Bus Stand, Vinayaka Mission University.
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RTC and private operators such as MVA Travels, Diya Bus, Kalyani Travels, Modern Travels, Greenline Kerala offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 699 - INR 1799.00 depending on the bus type and features.



